Biotin and derivatives
Medchemexpress LLC Mal-amido-PEG12-NHS ester | 2101722-60-3 | MFCD11041148 | 98.5% | C38H63N3O19 | 100 MG
Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.
- Protacs consist of two distinct ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest.
- Protacs leverage the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
Medchemexpress LLC IL-15 Human Biotin 10ug | 10ug
IL-15 protein regulates immune cells stimulates the proliferation of NK cells T cells and B cells and promotes cytokine secretion IL-15 Protein Human (Biotinylated HEK293 Fc-Avi) is the recombinant human-derived IL-15 protein expressed by HEK293 with C-Avi C-hFc labeled tag
Apexbio Technology LLC Cy5 NHS ester(Et) 25mg
Cy5 NHS ester (Et) is an amino-reactive fluorescent dye broadly utilized in biomedical research for labeling proteins peptides and antibodies via covalent conjugation to primary amines The reactive N-hydroxysuccinimidyl ester group specifically binds free amino groups forming stable conjugates suitable for fluorescence imaging and spectroscopic assays Its excitation and emission wavelengths (approximately 646 nm/662 nm) in the far-red spectrum enable compatibility with standard fluorescence microscopy techniques and flow cytometry Cy5 NHS ester (Et) conjugates are routinely employed in applications such as cellular imaging receptor-ligand binding assays protein localization studies and investigation of biomolecular interactions within research laboratory contexts
Medchemexpress LLC Biotin-PEG1-azide | 1204085-48-2 | 99.9% | 356.44 | C14H24N6O3S | 25 MG
Biotin-PEG1-azide is a biotinylated, single-unit polyethylene glycol (PEG) linker terminating in an azide functional group. It is used for bioconjugation and antibody-drug conjugate (ADC) synthesis through click chemistry reactions (CuAAC and SPAAC).
- Cleavable single-unit PEG linker for controlled spacing and solubility.
- Azide functional group enables CuAAC with alkynes and strain-promoted cycloaddition with DBCO/BCN.
- Suitable for ADC synthesis, protein labeling, and bioconjugation workflows.
- High purity (99.9%), characterized by H NMR, RP-HPLC, and MS.
- Available in small-scale packs for research use (e.g., 25 mg).
Medchemexpress LLC Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) | 138529-46-1 | 98.0% | 250 MG
Biotin-DADOO is a biotin-containing amine compound and a biotinylation reagent. As an amino component, it participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. It can be conjugated with carboxymethyl cellulose derivatives and is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A.
- Is a biotin-containing amine compound.
- Functions as a biotinylation reagent.
- Participates in nucleophilic ring-opening reactions during the synthesis of biotinylated inhibitor derivatives.
- Can be conjugated with carboxymethyl cellulose derivatives.
- Is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays.
- Can be used in the research of influenza A.
Medchemexpress LLC NKG2A Human Biotin 100ug | 100ug
The NKG2A protein is an important immunosuppressive receptor that forms a complex with KLRD1 on lymphocyte subsets for self-non-self discrimination It recognizes HLA-E loaded with self-peptides monitors MHC class I expression in healthy cells and promotes self-tolerance NKG2A Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived NKG2A protein expressed by HEK293 with N-His N-Avi labeled tag
Medchemexpress LLC NSP-SA-NHS | 199293-83-9 | 99.7% | 25 MG
NSP-SA-NHS is an acridinium ester designed for chemiluminescent immunoassay. It enables the development of rapid and sensitive immunoassays, such as for Bisphenol A (BPA) detection.
- Can be used for chemiluminescent immunoassay.
- A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed.
Apexbio Technology LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester 150206-05-6 5mg
5-Carboxyfluorescein diacetate N-succinimidyl ester (CAS 150206-05-6) is a fluorescent cell-permeable dye It is designed to enable stable cell labeling by facilitating intracellular conversion and covalent attachment to cellular amines 5-Carboxyfluorescein diacetate N-succinimidyl ester exerts its activity through membrane permeation intracellular esterase-mediated cleavage of acetate groups and subsequent covalent coupling to intracellular targets resulting in persistent fluorescence through cell division Based on these properties 5-Carboxyfluorescein diacetate N-succinimidyl ester holds research potential in tracking lymphocyte migration analyzing cell proliferation and investigating cell dynamics and interactions in various in vitro and in vivo experimental models
Medchemexpress LLC Azido-PEG9-NHS ester | 2801772-87-0 | 98.0% | C25H44N4O13 | 100 MG
Azido-PEG9-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It serves as a click chemistry reagent, featuring an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules. This ester can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Boc-NH-PEG2-C2-NHS ester | 2183440-73-3 | ≥98.0% | C16H26N2O8 | 500 MG
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are compounds designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins, functioning by connecting two ligands: one for an E3 ubiquitin ligase and one for the target protein. This compound appears as a white to off-white solid.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Enables selective degradation of target proteins
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC m-PEG24-NHS ester | 2395839-96-8 | 99.7% | 25 MG
m-PEG24-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins, offering a novel approach in therapeutic development. This product is intended for research use only and is supplied as a white to off-white solid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Stable under recommended storage conditions
eMolecules 58-85-5 | D-(+)-Biotin | Apollo Scientific US | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
D-(+)-Biotin | Apollo Scientific US | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
Medchemexpress LLC m-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 1 G
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands joined by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system to degrade target proteins
- Solid, white to off-white appearance
- For research use only
eMolecules 1807518-72-4 | Mal-PEG1-NHS ester | Ambeed | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Mal-PEG1-NHS ester | Ambeed | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Medchemexpress LLC m-PEG11-NHS ester | 3119903-67-9 | C28H51NO15 | 100 MG
m-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is recommended for storage at -20°C, sealed, and away from moisture and light. If in solvent, it can be stored at -80°C for 6 months or -20°C for 1 month, also with sealed storage, away from moisture and light.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Store at -20°C, sealed, away from moisture and light
- Extended storage in solvent possible at -80°C